Recurrent Hyperparathyroidism

Asymptomatic and Recurrent Hyperparathyroidism

Symptomatic Disease Bone disease in its florid form, osteitis fibrosa cystica generalizata, is now rarely seen. In 1947 Norris (1) found an incidence of this condition of 91% in those with a parathyroid adenoma. The earliest changes can be detected by X-rays of the hands where subperiosteal erosions can be detected in the phalanges (especially radial aspect of the middle phalanges) and terminal...

Recurrent Acute Pancreatitis: A Diagnostic Clue to Primary Hyperparathyroidism

Persistent or recurrent primary hyperparathyroidism.

More than 95% of patients with Primary Hyperparathyroidism (PHPT) are treated successfully at the initial operation when the operation is done by an experienced surgeon, but the success rate is considerably lower when done by an unexperienced surgeon. The approach to patients with persistent and recurrent PHPT is to confirm the diagnosis and to use precise localization procedures done by expert...

Recurrent renal hyperparathyroidism due to parathyromatosis

Parathyromatosis is the most severe type of recurrent secondary hyperparathyroidism (SHPT) after parathyroidectomy (PTX) in haemodialysis patients. It is difficult to completely remove all foci of parathyroid tissue and neck re-explorations are often required. Here, we report for the first time a case of recurrent SHPT due to parathyromatosis treated by radio-guided PTX. A haemodialysed 48-year...

Recurrent hyperparathyroidism due to parathyroid carcinoma.

The case is described of a woman who died with a functioning parathyroid carcinoma 19 years after removal of two parathyroid tumours, considered at the time to be benign. Following operation hyperparathyroidism subsided, with a short period of hypocalcaemia, and severe osteitis fibrosa cystica healed. Five years before death progressive renal failure developed with normal and later raised serum...